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Central GLP-1 contributes to improved cognitive function and brain glucose uptake after duodenum-jejunum bypass on obese and diabetic rats | American Journal of Physiology-Endocrinology and Metabolism | American Physiological Society
The Phase 3 TRIUMPH-4 trial enrolled 445 adults with obesity and knee osteoarthritis for 68 weeks
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It works through a hormone-based mechanism that targets appetite regulation rather than relying only on external diet or exercise interventions
