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The SURPASS-1 trial disclosed that fasting blood glucose levels rebounded to 20.2 mg/dL in the tirzepatide 5 mg group, 22.5 mg/dL in the 10 mg group, and 17.8 mg/dL in the 15 mg group over a four-week follow-up period after the end of tirzepatide administration [22]
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This accessibility is valuable, yet clinical depth varies significantly—some practices integrate metabolic screening and follow-up labs, while others provide minimal monitoring beyond initial prescription
